Depression is a kind of disturb in memory which has marked by deeply sadness and continually so it can make someone lost a passion to life. Teenage is heavy life period than the other age group. Depression and the other kind of psychology damage is always happened to teenager than adult. Objective : To know a difference depression level student who living at kos with student who living at home. Method : This study was Cross Sectional research using research subject namely 100 student of Medical Univercity of Muhammadiyah.This research used living stay and student report to know a difference level of depression.The questionnaire used BDI (Beck depression Inventory) and Crosstabs.After each variable data gained, then statistically test was conducted using Chi-Square Result and conclusion : The obtained research result using analytical test of P value=0,085 for difference level based at home.This research conclusion was no defference and correlation between living stay with depression level (P>0,005).