Congestive heart failure (CHF) is a progressive clinical syndrome caused by inability heart to pump sufficient blood to meet the body’s metabolic needs. Treatment of CHF varies widely in order to cause the incidence of drug related problems (DRPs), therefore the necessary of DRPs identification to achieve patient’s therapy outcome. The purpose of this study was to determine the description of therapy in patients with congestive heart failure as well as determine the incidence of drug related problems and to analyze drug related problems (DRPs). This is non-experimental descriptive study with retrospective data collection of 20 medical record with CHF during January to May 2015, then analyzed DRPs using literature analysis such as hospital standards of medical services, Pharmacotherapy Handbook 9th edition 2015, NYHA, Drug Interaction Facts and PERKI. In this study, there are 20 patients had 42 DRPs. The DRPs consist of 1 adverse drug reaction (2.38%), 26 drug choice problems (61.90%), 1 drug use problem (2.38%), 14 drug interactions (33.33%), and there is no dosing problem found.