Problem Based Learning (PBL) is a learning strategy by a problem or a case so that the students are able to think critically, suggest creative idea, communicate well. One of PBL components is skills lab. Skills lab is an activity in the laboratory to exercise the students pharmaceutical skills. The students activite participation on skills lab learning could be seen from how well the students master the materials and their communication ability. Communication is a process of delivering and receiving messages from one person to another. This study aims to discover the pharmacy students communication ability on skills lab learning. This study used descriptive analysis method using cross sectional approach. The pharmacy students communication skill was obtained from the questionnaire distribution which contained five indicators namely openness, empathy, supports, positive attitude and equality. Validity and reliability tests were conducted before the research by distributing the questionnaire to 30 respondents. The result of validity test showed that all questionnaire was valid in which r value was positive and r count > r table. The reliability test showed that it was reliable because the alfa cronbach was higher than 0.6 which was 0.926. After the questionnaire was considered as valid and reliable then it was distributed to 116 different respondents who were the students of batch 2012 and 2013. The result of the study showed the students who had good communication skill in skills lab learning were 76%, good enough communication 24% and poor communication 0%.