Background: Activity, frequency, and the kind of airplanes that operated went through a massive development as Adisucipto airport became an international airport. Right now, there are 25 regular flights from and to the airport. The impact of the development is the increasement of the noise intensity received by the citizens living around the airport. Noise exposure may head to physiological changes in a severe/chronic circumstance. Noise is considered as a stress, therefore, it may cause the increasement in blood pressure and disturbance in cardiovascular homeostasis. Postural change from supine to standing position is one of the ways to see the function of autonomic system. Method: ⁠ Observational with cross section. This study had 2 group subjects, the group receiving high intensity noise as the exposured one and the group receiving low intensity noise as the non-exposured one, with the quantity of 30 suitable subjects according to inclusion and exclusion criteria for each group. Data analysis was done using SPSS 15 for Windows Evaluation Version by testing the normality using kolmogorov smirnov and independent t test for data with normal distribution. Result: The result has shown that in high intensity noise as compared to low intensity noise group had significantly greater in systolic blood pressure (p < 0,05) in pretest (p value = 0,004), postest in 7 (p value = 0,02), delta between pretest and postest menit 1 (p value = 0,001). Diastolic blood pressure for the difference between 2 groups was borderline (p value= 0,05). MAP (mean arterial pressure), there were significantly greater in pretest (p value = 0,004) and delta menit 1 ( p value = 0,001). Pulse pressure the significantly greater result could be found in postest minute 7 (p value = 0,03) and delta minute 1 (p value= 0,017). Heart rate had borderline result within 7 minute in standing posisition. Conclusion: There is a difference in blood pressure response between the subjects living in a high noise intensity area and the subjects living in a low noise intensity area. Noise exposure chronically may influence homeostasis due to dysregulation, incomplete adaptation, or the effect of physiological adaptation. The consideration of decrease a higher blood pressure on the subjects receiving a high noise intensity or in a stress condition is related to sympathovagal reflex unstability.