Background: Increase the number of HIV / AIDS sufferers with the complexity that develops both spiritually, psychologically, and spiritually. Psychological problems caused by PLWHA overcoming difficulties, depression, guilt and the desire to end life that lead to ODHA have low self-esteem, social changes such as withdrawing from social life, changing roles, changing lifestyles and social alienation. Objective: to find out the feelings of people with HIV / AIDS (PLWHA) about diseases experienced in Yogyakarta. Method: This study uses a qualitative method with a phenomenological approach. Respondents in the study are 7 people. Data collected with in-depth interviews use instruments in the form of interview guides containing open questions. The analysis of the data in the study uses Cresswell's 13 steps system. Results: People with HIV / AIDS have a number of things to fear or worry about. The apprehensiveness experienced by PLWHA can cause certain responses. In addition, self-acceptance of PLWHA more or less affects the self-esteem of PLWHA. PLWHA who have high self-esteem can meet their own needs compared to ones who have low self-esteem. Someone who has low self-esteem tends to experience feelings as being unloved, psychological disorders such as stress and depression and the emergence of certain anxiety and worry. Conclusion: the feelings of PLWHA about their disease are apprehensiveness, responses of afraidness, bad acceptance, and less self-esteem.