This research aims to analyze the quality of service by using the method of Quality Function Deployment (QFD). The object of this research is PKU MuhammadiyahGamping Hospital which is located at Ambarketawangstreet, Sleman, Yogyakarta and the subject is former patient and visitor from RS PKU MuhammadiyahGamping. The way to improve the quality of service from the hospital is first we must know the wishes of its customers (Voice of Customer). Next, we need to find out what is the right solution to respond to Voice of Customer.This research uses primary data obtained by filling questionnaires and interviews. The sampling technique used is Purposive Sampling. The analytical tool used is House of Quality (HOQ). The result of this research is there are 32 attributes of Voice of Customer and 27 technical response from RS. Through the HOQ matrix, the technical response that should be prioritized for the improvement of PKU MuhammadiyahGamping Hospital is the response of clean room technique cleaned daily with score 80.