This research aims to study the perceptions of bussines actors on small industry center to business climate in Sleman District. This research uses primary and secondary data through observation, literature study and questionnaire to 94 business actors of small industry center in Sleman District. 94 respondents is selected by random sampling and descriptive analysis as the data analysis technique. The result analysis describes the business climate in Sleman District is conducive. Generally, business actors have a good-knowledge in business climate. From the research result, we know that the political and social stability factor (18,9%) is considered the most dominant factor as a determinant of business climate, followed by second, order infrastructure factors (18,9%), third, government policy factor (18,9%) and fourth, bureaucratic(16,4%) and financial system factor (16,2%).