HUBUNGAN RIWAYAT ATOPI TERHADAP POLA SENSIVITAS HASIL TES UJI CUKIT KULIT (SKIN PRICK TEST)
Abstract
Background : Atopic is a genetic predisposition of developing hyper sensitivity
after the exposure to certain allergens which is characterized by elevated IgE
antibodies in the circulation There is an increased prevalence of atopy happened
in developing countries compared to developed countries due to changes of
environment and lifestyle. Atopy is caused not only by the changes of the
environment and lifestyle, but also by genetic factors. Atopic disease is considered
as a minor disease and it is commonly found in children. However, it can also
affect the health status, quality of life, and mortality of a person.
Metode : This study used an observational research design with cross sectional
approach to assess the correlation between atopic history and the sensitivity
pattern of skin prict test. In a cross-sectional study, the researchers observed or
measured the variables at one time. There were 86 children aged 10-12 years old
from two different primary schools.
Results: Subjects with atopic history were classified into 3 groups: groups with a
history of Allergic Rhinitis, Asthma and Atopic Dermatitis and food allergies.
There was a positive skin prick test result, that is 29 children (47.5%), with
significance (p=0.363) for subjects with a history of allergic rhinitis, while for
subjects with Asthma history, a positive skin prick test results of 11 children
(18.0%) was obtained, with significance (p=0,000). Moreover, subjects with a
history of Atopic Dermatits, a positive skin prick test results of 12 children
(19.7%) was also obtained with significance (p = 0,000) and at last, subjects with
a history of food allergy, a positive skin prick test results obtained was 8 children
(13,1%) with signification (p = 0,000).
Conclusion: It can be concluded that there is a correlation between atopic history
and the sensitivity patterns of skin prick test for the subjects being examined.